ACTN3 antibody (C-Term) (HRP)

Catalog No. ABIN7965732

The HRP-conjugated Mouse Monoclonal anti-ACTN3 antibody (Clone 9B5) (ABIN7965732) specifically detects ACTN3 in WB, ELISA and IHC. The antibody is reactive with Mouse and Rat samples.

Quick Overview for ACTN3 antibody (C-Term) (HRP) (ABIN7965732)

Target: ACTN3 (Actinin, alpha 3 (ACTN3))

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACTN3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 9B5

Product Details anti-ACTN3 Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-ACTN3 Antibody (monoclonal, 9B5) HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by five amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ACTN3, different from the related mouse sequence by five amino acids.

Isotype: IgG1

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ACTN3

Target: ACTN3 (Actinin, alpha 3 (ACTN3))

Alternative Name: ACTN3

Background:

Background: Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants, the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.

Gene Full Name: actinin alpha 3

Gene ID: 89

UniProt: Q08043

Pathways: Cell-Cell Junction Organization