ABR antibody (Middle Region) (Fluoro550)

Catalog No. ABIN7965971

The Rabbit Polyclonal anti-ABR antibody is suitable to detect ABR in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for ABR antibody (Middle Region) (Fluoro550) (ABIN7965971)

Target: ABR (Active BCR-Related (ABR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABR antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-ABR Antibody (Fluoro550)

Binding Specificity: Middle Region

Purpose: Anti-ABR Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ABR, different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ABR

Target: ABR (Active BCR-Related (ABR))

Alternative Name: ABR

Background:

Background: This ABR gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.

Gene Full Name: ABR activator of RhoGEF and GTPase

Gene ID: 29

UniProt: Q12979

Pathways: Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity