ABR antibody (AA 180-859) (Biotin)

Catalog No. ABIN7965979

This Rabbit Polyclonal antibody specifically detects ABR in ELISA, WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ABR antibody (AA 180-859) (Biotin) (ABIN7965979)

Target: ABR (Active BCR-Related (ABR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABR antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ABR Antibody (Biotin)

Binding Specificity: AA 180-859

Purpose: Anti-ABR Antibody Biotin Conjugated

Predicted Reactivity: Human ABR shares 99.3% amino acid (aa) sequence identity with both mouse,rat ABR.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ABR recombinant protein (Position: Q180-V859). Human ABR shares 99.3% amino acid (aa) sequence identity with both mouse and rat ABR.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ABR

Target: ABR (Active BCR-Related (ABR))

Alternative Name: ABR

Background:

Background: This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.

Gene Full Name: ABR activator of RhoGEF and GTPase

Gene ID: 29

UniProt: Q12979

Pathways: Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity