ACOX1 antibody (AA 605-648) (Fluoro647)

Catalog No. ABIN7966109

The Rabbit Polyclonal anti-ACOX1 antibody is suitable to detect ACOX1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for ACOX1 antibody (AA 605-648) (Fluoro647) (ABIN7966109)

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOX1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-ACOX1 Antibody (Fluoro647)

Binding Specificity: AA 605-648

Purpose: Anti-ACOX1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human ACOX1shares 93.2%,90.9% amino acid (aa) sequence identity with mouse,rat ACOX1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ACOX1 recombinant protein (Position: A605-E648). Human ACOX1shares 93.2% and 90.9% amino acid (aa) sequence identity with mouse and rat ACOX1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ACOX1

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Alternative Name: ACOX1

Background:

Background: The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: acyl-CoA oxidase 1

Gene ID: 51

UniProt: Q15067

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process