ADAM12 antibody (AA 31-476) (Fluoro594)

Catalog No. ABIN7966247

The Rabbit Polyclonal anti-ADAM12 antibody is suitable to detect ADAM12 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for ADAM12 antibody (AA 31-476) (Fluoro594) (ABIN7966247)

Target: ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM12 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-ADAM12 Antibody (Fluoro594)

Binding Specificity: AA 31-476

Purpose: Anti-ADAM12 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human ADAM12 shares 79.1% amino acid (aa) sequence identity with mouse ADAM12.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ADAM12 recombinant protein (Position: V31-K476). Human ADAM12 shares 79.1% amino acid (aa) sequence identity with mouse ADAM12.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ADAM12

Target: ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Alternative Name: ADAM12

Background:

Background: This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.

Gene Full Name: ADAM metallopeptidase domain 12

Gene ID: 8038

UniProt: O43184

Pathways: EGFR Signaling Pathway