ADAM2 antibody (AA 228-277) (Cy3)

Catalog No. ABIN7966310

The Rabbit Polyclonal anti-ADAM2 antibody is suitable to detect ADAM2 in samples from Human. It has been validated for FACS.

Quick Overview for ADAM2 antibody (AA 228-277) (Cy3) (ABIN7966310)

Target: ADAM2 (ADAM Metallopeptidase Domain 2 (ADAM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM2 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-ADAM2 Antibody (Cy3)

Binding Specificity: AA 228-277

Purpose: Anti-ADAM2 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human ADAM2 shares 72% amino acid (aa) sequence identity with both mouse,rat ADAM2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ADAM2 recombinant protein (Position: L228-Y277). Human ADAM2 shares 72% amino acid (aa) sequence identity with both mouse and rat ADAM2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ADAM2

Target: ADAM2 (ADAM Metallopeptidase Domain 2 (ADAM2))

Alternative Name: ADAM2

Background:

Background: Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: ADAM metallopeptidase domain 2

Gene ID: 2515

UniProt: Q99965