ADAR antibody (AA 1-1152) (Fluoro488)

Catalog No. ABIN7966685

The Rabbit Polyclonal anti-ADAR antibody is suitable to detect ADAR in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for ADAR antibody (AA 1-1152) (Fluoro488) (ABIN7966685)

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAR antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-ADAR Antibody (Fluoro488)

Binding Specificity: AA 1-1152

Purpose: Anti-ADAR1/ADAR Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ADAR1/ADAR recombinant protein (Position: M1-E1152).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ADAR

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Alternative Name: ADAR

Background:

Background: Double-stranded RNA-specific adenosine deaminase is an enzyme that in humans is encoded by the ADAR gene. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

Gene Full Name: adenosine deaminase RNA specific

Gene ID: 103

UniProt: P55265

Pathways: Protein targeting to Nucleus