ADRM1 antibody (AA 15-390) (Cy3)

Catalog No. ABIN7966849

This Rabbit Polyclonal antibody specifically detects ADRM1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADRM1 antibody (AA 15-390) (Cy3) (ABIN7966849)

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRM1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-ADRM1 Antibody (Cy3)

Binding Specificity: AA 15-390

Purpose: Anti-ADRM1/ARM-1 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ADRM1/ARM-1 recombinant protein (Position: S15-K390).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Alternative Name: ADRM1

Background:

Background: Proteasomal ubiquitin receptor ADRM1 is a protein that in humans is encoded by the ADRM1 gene. This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an in effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.

Gene Full Name: ADRM1 26S proteasome ubiquitin receptor

Gene ID: 11047

UniProt: Q16186

Pathways: Positive Regulation of Endopeptidase Activity