AFF4 antibody (N-Term) (Cy3)

Catalog No. ABIN7967157

The Cy3-conjugated Mouse Monoclonal anti-AFF4 antibody (Clone 8G12) (ABIN7967157) specifically detects AFF4 in FACS. The antibody is reactive with Human samples.

Quick Overview for AFF4 antibody (N-Term) (Cy3) (ABIN7967157)

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AFF4 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Clone: 8G12

Product Details anti-AFF4 Antibody (Cy3)

Binding Specificity: N-Term

Purpose: Anti-AFF4 Antibody (monoclonal, 8G12) Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequence.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human AFF4, identical to the related mouse sequence.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AFF4

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Alternative Name: AFF4

Background:

Background: The AFF4 gene encodes a scaffold protein that functions as a core component of the super elongation complex (SEC), which is involved in transcriptional regulation during embryogenesis. The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. This gene is mapped to chromosome 5q31.

Gene Full Name: ALF transcription elongation factor 4

Gene ID: 27125

UniProt: Q9UHB7