ALT antibody (AA 2-496) (Fluoro647)

Catalog No. ABIN7967253

The Fluoro647-conjugated Rabbit Polyclonal anti-ALT antibody (ABIN7967253) specifically detects ALT in FACS. The antibody is reactive with Rat and Mouse samples.

Quick Overview for ALT antibody (AA 2-496) (Fluoro647) (ABIN7967253)

Target: ALT (Alanine Aminotransferase (ALT))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALT antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-ALT Antibody (Fluoro647)

Binding Specificity: AA 2-496

Purpose: Anti-Alanine Transaminase/Gpt Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Alanine Transaminase/Gpt recombinant protein (Position: A2-S496).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ALT

Target: ALT (Alanine Aminotransferase (ALT))

Alternative Name: Gpt

Background:

Background: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1), also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase

Gene Full Name: glutamic pyruvic transaminase, soluble

Gene ID: 76282

UniProt: Q8QZR5