APLP2 antibody (C-Term) (Fluoro647)

Catalog No. ABIN7968309

The Fluoro647-conjugated Rabbit Polyclonal anti-APLP2 antibody (ABIN7968309) specifically detects APLP2 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for APLP2 antibody (C-Term) (Fluoro647) (ABIN7968309)

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-APLP2 Antibody (Fluoro647)

Binding Specificity: C-Term

Purpose: Anti-Amyloid-like protein 2 APLP2 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related rat,mouse sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human APLP2, different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Alternative Name: APLP2

Background:

Background: APLP2 (Amyloid beta (A4) precursor-like protein 2), also known as CDEBP or SPERM MEMBRANE PROTEIN, is a protein that in humans is encoded by the APLP2 gene. The APLP2 gene is mapped on 11q24.3. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. APLP2 along with APLP1 are important modulators of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.

Gene Full Name: amyloid beta precursor like protein 2

Sequence Similarities: Belongs to the APP family.

Gene ID: 334

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour