ANG antibody (AA 25-147) (Biotin)

Catalog No. ABIN7968421

This Rabbit Polyclonal antibody specifically detects ANG in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for ANG antibody (AA 25-147) (Biotin) (ABIN7968421)

Target: ANG (Angiogenin (ANG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANG antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-ANG Antibody (Biotin)

Binding Specificity: AA 25-147

Purpose: Anti-Angiogenin/ANG Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human Angiogenin,ANG recombinant protein (Position: Q25-P147). Human Angiogenin,ANG shares 77.5% amino acid (aa) sequence identity with mouse Angiogenin,ANG.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Angiogenin/ANG recombinant protein (Position: Q25-P147). Human Angiogenin/ANG shares 77.5% amino acid (aa) sequence identity with mouse Angiogenin/ANG.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ANG

Target: ANG (Angiogenin (ANG))

Alternative Name: ANG

Background:

Background: Angiogenin (Ang), also known as ribonuclease 5, is a small 123 amino acid protein that in humans is encoded by the ANG gene. The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.

Gene Full Name: angiogenin

Gene ID: 283

UniProt: P03950