ANG antibody (AA 25-147) (Fluoro594)

Catalog No. ABIN7968425

The Rabbit Polyclonal anti-ANG antibody is suitable to detect ANG in samples from Human. It has been validated for FACS.

Quick Overview for ANG antibody (AA 25-147) (Fluoro594) (ABIN7968425)

Target: ANG (Angiogenin (ANG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANG antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-ANG Antibody (Fluoro594)

Binding Specificity: AA 25-147

Purpose: Anti-Angiogenin/ANG Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human Angiogenin,ANG recombinant protein (Position: Q25-P147). Human Angiogenin,ANG shares 77.5% amino acid (aa) sequence identity with mouse Angiogenin,ANG.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Angiogenin/ANG recombinant protein (Position: Q25-P147). Human Angiogenin/ANG shares 77.5% amino acid (aa) sequence identity with mouse Angiogenin/ANG.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ANG

Target: ANG (Angiogenin (ANG))

Alternative Name: ANG

Background:

Background: Angiogenin (Ang), also known as ribonuclease 5, is a small 123 amino acid protein that in humans is encoded by the ANG gene. The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.

Gene Full Name: angiogenin

Gene ID: 283

UniProt: P03950