Angiomotin antibody (AA 12-622) (Fluoro647)

Catalog No. ABIN7968452

The Rabbit Polyclonal anti-Angiomotin antibody is suitable to detect Angiomotin in samples from Human. It has been validated for FACS.

Quick Overview for Angiomotin antibody (AA 12-622) (Fluoro647) (ABIN7968452)

Target: Angiomotin (AMOT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiomotin antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Angiomotin Antibody (Fluoro647)

Binding Specificity: AA 12-622

Purpose: Anti-Angiomotin/AMOT Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Angiomotin/AMOT recombinant protein (Position: T12-Q622).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Angiomotin

Target: Angiomotin (AMOT)

Alternative Name: AMOT

Background:

Background: Angiomotin (AMOT) is a protein that in humans is encoded by the AMOT gene. This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: angiomotin

Gene ID: 154796

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size