ANKRD1 antibody (AA 120-319) (APC)

Catalog No. ABIN7968802

This Rabbit Polyclonal antibody specifically detects ANKRD1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ANKRD1 antibody (AA 120-319) (APC) (ABIN7968802)

Target: ANKRD1 (Ankyrin Repeat Domain 1 (Cardiac Muscle) (ANKRD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-ANKRD1 Antibody (APC)

Binding Specificity: AA 120-319

Purpose: Anti-ANKRD1 Antibody APC Conjugated

Predicted Reactivity: Human ANKRD1 shares 93.5%,95% amino acid (aa) sequence identity with mouse,rat ANKRD1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ANKRD1 recombinant protein (Position: D120-F319). Human ANKRD1 shares 93.5% and 95% amino acid (aa) sequence identity with mouse and rat ANKRD1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ANKRD1

Target: ANKRD1 (Ankyrin Repeat Domain 1 (Cardiac Muscle) (ANKRD1))

Alternative Name: ANKRD1

Background:

Background: Ankyrin repeat domain-containing protein 1, or Cardiac ankyrin repeat protein is a protein that in humans is encoded by the ANKRD1 gene also known as CARP. The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.

Gene Full Name: ankyrin repeat domain 1

Gene ID: 27063

UniProt: Q15327

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Response to DNA Damage Stimulus