Annexin A3 antibody (Middle Region) (Fluoro594)

Catalog No. ABIN7968931

The Mouse Monoclonal anti-Annexin A3 antibody is suitable to detect Annexin A3 in samples from Human. It has been validated for FACS.

Quick Overview for Annexin A3 antibody (Middle Region) (Fluoro594) (ABIN7968931)

Target: Annexin A3 (ANXA3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin A3 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Clone: 2H3H8

Product Details anti-Annexin A3 Antibody (Fluoro594)

Binding Specificity: Middle Region

Purpose: Anti-Annexin A3 Antibody (monoclonal, 2H3H8) Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by one amino acid,and from the related rat sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Annexin A3, different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Annexin A3

Target: Annexin A3 (ANXA3)

Alternative Name: ANXA3

Background:

Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Gene Full Name: annexin A3

Gene ID: 306

UniProt: P12429