Annexin V antibody (AA 2-320) (Cy3)

Catalog No. ABIN7968994

The Rabbit Polyclonal anti-Annexin V antibody is suitable to detect Annexin V in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Annexin V antibody (AA 2-320) (Cy3) (ABIN7968994)

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin V antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-Annexin V Antibody (Cy3)

Binding Specificity: AA 2-320

Purpose: Anti-Annexin V/ANXA5 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Annexin V shares 94%,92% amino acid (aa) sequences identity with mouse,rat Annexin V,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Annexin V recombinant protein (Position: A2-D320). Human Annexin V shares 94% and 92% amino acid (aa) sequences identity with mouse and rat Annexin V, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Annexin V

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Alternative Name: ANXA5

Background:

Background: Annexin A5 (or annexin V) is a cellular protein in the annexin group. It is mapped to 4q27. Annexin A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. This protein is an anticoagulant protein, it can form a shield around negatively-charged phospholipid molecules, the formation of an annexin A5 shield blocks the entry of phospholipids into coagulation (clotting) reactions. And Annexin A5 can also act as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

Gene Full Name: annexin A5

Sequence Similarities: Belongs to the annexin family.

Gene ID: 308

UniProt: P08758

Pathways: Apoptosis