Annexin VII antibody (C-Term) (Fluoro647)

Catalog No. ABIN7969046

The Fluoro647-conjugated Rabbit Polyclonal anti-Annexin VII antibody (ABIN7969046) specifically detects Annexin VII in FACS. The antibody is reactive with Human samples.

Quick Overview for Annexin VII antibody (C-Term) (Fluoro647) (ABIN7969046)

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VII antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Annexin VII Antibody (Fluoro647)

Binding Specificity: C-Term

Purpose: Anti-Annexin VII/ANXA7 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Annexin VII, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Alternative Name: ANXA7

Background:

Background: ANXA7 (Annexin A7), also known as ANX7 or SNX, is a protein that in humans is encoded by the ANXA7 gene. Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins. Shirvan et al. (1994) isolated genomic clones of the ANXA7 gene and assigned the gene to 10q21.1-q21.2 by study of somatic cell hybrids and by in situ hybridization. Srivastava et al. (2001) concluded that the ANX7 gene exhibits many biologic and genetic properties expected of a tumor suppressor gene and may play a role in prostate cancer progression. Caohuy et al. (1996) present experimental evidence, based on studies of recombinant human ANXA7 and isolated bovine chromaffin cells, that ANXA7 is a Ca (2+)-dependent GTP binding protein. ANXA7 was active in a chromaffin granule aggregation assays in the presence of Ca (2+) and GTP, and was deactivated upon GTP hydrolysis.

Gene Full Name: annexin A7

Sequence Similarities: Belongs to the annexin family.

Gene ID: 310

UniProt: P20073