AMH antibody (AA 75-141) (Fluoro647)

Catalog No. ABIN7969134

This Rabbit Polyclonal antibody specifically detects AMH in FACS. It exhibits reactivity toward Human.

Quick Overview for AMH antibody (AA 75-141) (Fluoro647) (ABIN7969134)

Target: AMH (Anti-Mullerian Hormone (AMH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMH antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-AMH Antibody (Fluoro647)

Binding Specificity: AA 75-141

Purpose: Anti-AMH Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human AMH shares 66.7% amino acid (aa) sequence identity with both mouse,rat AMH.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AMH recombinant protein (Position: A75-E141). Human AMH shares 66.7% amino acid (aa) sequence identity with both mouse and rat AMH.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Alternative Name: AMH

Background:

Background: Anti-Müllerian hormone (AMH), also known as MIF or MIS, is a protein that in humans is encoded by the AMH gene. It is a hormone that inhibits the development of the Müllerian ducts (paramesonephric ducts) in the male embryo. Expression of AMH is activated by SOX9 in the male Sertoli cells and causes the irreversible regression of the Müllerian ducts. Because AMH expression is critical to sex differentiation at a specific time during fetal development, it appears to be tightly regulated by SF1, GATA factors, DAX1 and FSH. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.

Gene Full Name: anti-Mullerian hormone

Gene ID: 268

UniProt: P03971

Pathways: Negative Regulation of Hormone Secretion