AQP11 antibody (AA 30-57) (Fluoro647)

Catalog No. ABIN7969651

The Rabbit Polyclonal anti-AQP11 antibody is suitable to detect AQP11 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for AQP11 antibody (AA 30-57) (Fluoro647) (ABIN7969651)

Target: AQP11 (Aquaporin 11 (AQP11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP11 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-AQP11 Antibody (Fluoro647)

Binding Specificity: AA 30-57

Purpose: Anti-AQP11 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AQP11 recombinant protein (Position: L30-L57).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AQP11

Target: AQP11 (Aquaporin 11 (AQP11))

Alternative Name: AQP11

Background:

Background: AQP11 has a unique asparagine-proline-alanine (NPA) box distinct from those of other AQPs, suggesting a different pore structure and function. Using Northern blot analysis, they detected highest expression of mouse Aqp11 in testis, followed by liver and kidney. Expression was much weaker in heart, brain, and muscle. Western blot analysis of mouse kidney membrane fractions detected Aqp11 at an apparent molecular mass of 26 kD, lower than the calculated molecular mass of 30 kD. Immunohistochemical analysis localized Aqp11 to mouse renal proximal tubule cells, where it showed a perinuclear distribution. Fluorescence-tagged Aqp11 localized with an endoplasmic reticulum marker.

Gene Full Name: aquaporin 11

Gene ID: 282679

UniProt: Q8NBQ7