AQP6 antibody (C-Term) (HRP)

Catalog No. ABIN7969769

The HRP-conjugated Rabbit Polyclonal anti-AQP6 antibody (ABIN7969769) specifically detects AQP6 in ELISA, WB and IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for AQP6 antibody (C-Term) (HRP) (ABIN7969769)

Target: AQP6 (Aquaporin 6, Kidney Specific (AQP6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP6 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AQP6 Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-Aquaporin 6/AQP6 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequences by fourteen amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6, different from the related mouse and rat sequences by fourteen amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AQP6

Target: AQP6 (Aquaporin 6, Kidney Specific (AQP6))

Alternative Name: AQP6

Background:

Background: Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins (AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.

Gene Full Name: aquaporin 6

Gene ID: 363

UniProt: Q13520