AVPR1A antibody (Middle Region) (FITC)

Catalog No. ABIN7970010

This Rabbit Polyclonal antibody specifically detects AVPR1A in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for AVPR1A antibody (Middle Region) (FITC) (ABIN7970010)

Target: AVPR1A (Arginine Vasopressin Receptor 1A (AVPR1A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR1A antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-AVPR1A Antibody (FITC)

Binding Specificity: Middle Region

Purpose: Anti-Vasopressin V1a receptor AVPR1A Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related human,mouse sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of rat AVPR1A, different from the related human and mouse sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AVPR1A

Target: AVPR1A (Arginine Vasopressin Receptor 1A (AVPR1A))

Alternative Name: AVPR1A

Background:

Background: Arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for arginine vasopressin  (AVPR1B and AVPR2 being the others). It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

Gene Full Name: arginine vasopressin receptor 1A

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Gene ID: 25107

UniProt: P30560

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Response to Water Deprivation, Regulation of Carbohydrate Metabolic Process