AHRR antibody (AA 410-665) (Biotin)

Catalog No. ABIN7970313

This Rabbit Polyclonal antibody specifically detects AHRR in ELISA, WB and IHC. It exhibits reactivity toward Human.

Quick Overview for AHRR antibody (AA 410-665) (Biotin) (ABIN7970313)

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHRR antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AHRR Antibody (Biotin)

Binding Specificity: AA 410-665

Purpose: Anti-AHRR Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AHRR recombinant protein (Position: K410-D665).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AHRR

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Alternative Name: AHRR

Background:

Background: The aryl-hydrocarbon receptor repressor also known as AHRR is a human gene. The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: aryl hydrocarbon receptor repressor

Gene ID: 57491

UniProt: A9YTQ3

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha