Arylsulfatase B antibody (C-Term) (Fluoro488)

Catalog No. ABIN7970348

The Fluoro488-conjugated Rabbit Polyclonal anti-Arylsulfatase B antibody (ABIN7970348) specifically detects Arylsulfatase B in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Arylsulfatase B antibody (C-Term) (Fluoro488) (ABIN7970348)

Target: Arylsulfatase B (ARSB)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arylsulfatase B antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Arylsulfatase B Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-Arsb Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Arsb, which shares 88.2% and 94.1% amino acid (aa) sequence identity with human and rat Arsb, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Arylsulfatase B

Target: Arylsulfatase B (ARSB)

Alternative Name: Arsb

Background:

Background: Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

Gene Full Name: arylsulfatase B

Gene ID: 11881

UniProt: P50429

Pathways: Glycosaminoglycan Metabolic Process