DARS2 antibody (AA 334-448) (Fluoro488)

Catalog No. ABIN7970427

This Rabbit Polyclonal antibody specifically detects DARS2 in FACS. It exhibits reactivity toward Human.

Quick Overview for DARS2 antibody (AA 334-448) (Fluoro488) (ABIN7970427)

Target: DARS2 (Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DARS2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-DARS2 Antibody (Fluoro488)

Binding Specificity: AA 334-448

Purpose: Anti-DARS2 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DARS2 recombinant protein (Position: D334-A448).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DARS2

Target: DARS2 (Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

Alternative Name: DARS2

Background:

Background: DARS2 contains conserved residues involved in ATP binding, tRNA binding, and aspartic acid recognition, as well as catalytic site motifs characteristic of amino acid tRNA synthetases. The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). The International Radiation Hybrid Mapping Consortium mapped the DARS2 gene to chromosome 1.

Gene Full Name: aspartyl-tRNA synthetase 2, mitochondrial

Gene ID: 55157

UniProt: Q6PI48