Ataxin 1 antibody (C-Term) (Cy3)

Catalog No. ABIN7970514

This Rabbit Polyclonal antibody specifically detects Ataxin 1 in FACS. It exhibits reactivity toward Mouse, Human and Rat.

Quick Overview for Ataxin 1 antibody (C-Term) (Cy3) (ABIN7970514)

Target: Ataxin 1 (ATXN1)

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-Ataxin 1 Antibody (Cy3)

Binding Specificity: C-Term

Purpose: Anti-Ataxin 1/ATXN1 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Ataxin 1, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Ataxin 1

Target: Ataxin 1 (ATXN1)

Alternative Name: ATXN1

Background:

Background: Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.

Gene Full Name: ataxin 1

Sequence Similarities: Belongs to the ATXN1 family.

UniProt: P54253

Pathways: Synaptic Membrane