Ataxin 2 antibody (C-Term) (Fluoro594)

Catalog No. ABIN7970539

The Rabbit Polyclonal anti-Ataxin 2 antibody is suitable to detect Ataxin 2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Ataxin 2 antibody (C-Term) (Fluoro594) (ABIN7970539)

Target: Ataxin 2 (ATXN2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-Ataxin 2 Antibody (Fluoro594)

Binding Specificity: C-Term

Purpose: Anti-ATX2/ATXN2 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related mouse sequence.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ATX2, identical to the related mouse sequence.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Ataxin 2

Target: Ataxin 2 (ATXN2)

Alternative Name: ATXN2

Background:

Background: Ataxin-2, the protein encoded by the ATXN2 gene, contains a polyglutamine tract, long expansions (greater than 33 repeats) of which result in spinocerebellar ataxia-2 (SCA2), an autosomal dominant form of olivopontocerebellar atrophy. The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24.1. Ataxin-2 associates with L- and T-plastin and that overexpression of ataxin-2 leads to accumulation of T-plastin in mammalian cells.

Gene Full Name: ataxin 2

Sequence Similarities: Belongs to the ATG14 family.

UniProt: Q99700

Pathways: Ribonucleoprotein Complex Subunit Organization