ATG7 antibody (AA 71-645) (Fluoro550)

Catalog No. ABIN7970659

The Rabbit Polyclonal anti-ATG7 antibody is suitable to detect ATG7 in samples from Human. It has been validated for FACS.

Quick Overview for ATG7 antibody (AA 71-645) (Fluoro550) (ABIN7970659)

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG7 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-ATG7 Antibody (Fluoro550)

Binding Specificity: AA 71-645

Purpose: Anti-ATG7 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human ATG7 shares 92.9% amino acid (aa) sequence identity with both mouse,rat ATG7.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ATG7 recombinant protein (Position: D71-K645). Human ATG7 shares 92.9% amino acid (aa) sequence identity with both mouse and rat ATG7.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Alternative Name: ATG7

Background:

Background: Autophagy related 7 is a protein in humans encoded by ATG7 gene. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

Gene Full Name: autophagy related 7

Gene ID: 10533

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagy