ATL1 antibody (Middle Region) (PE)

Catalog No. ABIN7970708

The PE-conjugated Rabbit Polyclonal anti-ATL1 antibody (ABIN7970708) specifically detects ATL1 in FACS. The antibody is reactive with Human samples.

Quick Overview for ATL1 antibody (Middle Region) (PE) (ABIN7970708)

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATL1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-ATL1 Antibody (PE)

Binding Specificity: Middle Region

Purpose: Anti-SPG3A/ATL1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SPG3A/ATL1, which shares 93.8% and 100% amino acid (aa) sequence identity with mouse and rat ATL1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ATL1

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Alternative Name: ATL1

Background:

Background: Atlastin, or Atlastin-1, is a protein that in humans is encoded by the ATL1 gene. The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Gene Full Name: atlastin GTPase 1

Gene ID: 51062

UniProt: Q8WXF7