ATOH1 antibody (N-Term) (PE)

Catalog No. ABIN7970730

This Rabbit Polyclonal antibody specifically detects ATOH1 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for ATOH1 antibody (N-Term) (PE) (ABIN7970730)

Target: ATOH1 (Atonal Homolog 1 (Drosophila) (ATOH1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATOH1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-ATOH1 Antibody (PE)

Binding Specificity: N-Term

Purpose: Anti-MATH1/HATH1/ATOH1 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MATH1/HATH1, different from the related mouse sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ATOH1

Target: ATOH1 (Atonal Homolog 1 (Drosophila) (ATOH1))

Alternative Name: ATOH1

Background:

Background: Protein atonal homolog 1 is a protein that in humans is encoded by the ATOH1 gene. This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. ATOH1 is required for the formation of both neural and non-neural cell types. Using genetic deletion in mice, Atoh1 has been shown to be essential for formation of cerebellar granule neurons, inner ear hair cells, spinal cord interneurons, Merkel cells of the skin, and intestinal secretory cells (goblet, enteroendocrine, and Paneth cells).

Gene Full Name: atonal bHLH transcription factor 1

Gene ID: 474

UniProt: Q92858