BCL11B antibody (AA 10-628) (APC)

Catalog No. ABIN7971853

The Rabbit Polyclonal anti-BCL11B antibody is suitable to detect BCL11B in samples from Human and Rat. It has been validated for FACS.

Quick Overview for BCL11B antibody (AA 10-628) (APC) (ABIN7971853)

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL11B antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-BCL11B Antibody (APC)

Binding Specificity: AA 10-628

Purpose: Anti-BCL11B Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BCL11B recombinant protein (Position: Q10-A628).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for BCL11B

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Alternative Name: BCL11B

Background:

Background: B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene. This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Full Name: BCL11 transcription factor B

Gene ID: 64919

UniProt: Q9C0K0