BCL11B antibody (AA 10-628)

Catalog No. ABIN7971856

The Rabbit Polyclonal anti-BCL11B antibody is suitable to detect BCL11B in samples from Human and Rat. It has been validated for WB, ELISA, IHC, FACS, IF and ICC.

Quick Overview for BCL11B antibody (AA 10-628) (ABIN7971856)

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL11B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-BCL11B Antibody

Binding Specificity: AA 10-628

Purpose: Anti-BCL11B Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-BCL11B Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BCL11B recombinant protein (Position: Q10-A628).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg /1x10⁶ cells, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCL11B

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Alternative Name: BCL11B

Background:

Background: B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene. This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Full Name: BCL11 transcription factor B

Molecular Weight: 116 kDa

Gene ID: 64919

UniProt: Q9C0K0