BAG1 antibody (C-Term) (Fluoro550)

Catalog No. ABIN7972291

The Rabbit Polyclonal anti-BAG1 antibody is suitable to detect BAG1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for BAG1 antibody (C-Term) (Fluoro550) (ABIN7972291)

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAG1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-BAG1 Antibody (Fluoro550)

Binding Specificity: C-Term

Purpose: Anti-Bag1 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by two amino acids,and from the related rat sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Bag1, different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for BAG1

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Alternative Name: BAG1

Background:

Background: BAG family molecular chaperone regulator 1 (BAG1) is a protein that in humans is encoded by the BAG1 gene. Human BAG1 is mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The Bag1 protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.

Gene Full Name: BAG cochaperone 1

Gene ID: 573

UniProt: Q99933