BCLAF1 antibody (AA 293-901) (Biotin)

Catalog No. ABIN7972376

The Biotin-conjugated Rabbit Polyclonal anti-BCLAF1 antibody (ABIN7972376) specifically detects BCLAF1 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BCLAF1 antibody (AA 293-901) (Biotin) (ABIN7972376)

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCLAF1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-BCLAF1 Antibody (Biotin)

Binding Specificity: AA 293-901

Purpose: Anti-BCLAF1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human BCLAF1 shares 94.4% amino acid (aa) sequence identity with mouse BCLAF1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BCLAF1 recombinant protein (Position: H293-E901). Human BCLAF1 shares 94.4% amino acid (aa) sequence identity with mouse BCLAF1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: BCLAF1

Background:

Background: This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: BCL2 associated transcription factor 1

Gene ID: 9774

UniProt: Q9NYF8

Pathways: Positive Regulation of Response to DNA Damage Stimulus