BCCIP antibody (AA 167-300)

Catalog No. ABIN7973179

The Rabbit Polyclonal anti-BCCIP antibody is suitable to detect BCCIP in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA, IF, FACS and ICC.

Quick Overview for BCCIP antibody (AA 167-300) (ABIN7973179)

Target: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCCIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-BCCIP Antibody

Binding Specificity: AA 167-300

Purpose: Anti-BCCIP Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-BCCIP Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BCCIP recombinant protein (Position: K167-K300).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCCIP

Target: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Alternative Name: BCCIP

Background:

Background: BRCA2 and CDKN1A-interacting protein is a protein that in humans is encoded by the BCCIP gene. This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: BRCA2 and CDKN1A interacting protein

Molecular Weight: 45 kDa

Gene ID: 56647

UniProt: Q9P287