BRMS1 antibody (AA 52-244) (Fluoro550)

Catalog No. ABIN7973260

The Rabbit Polyclonal anti-BRMS1 antibody is suitable to detect BRMS1 in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for BRMS1 antibody (AA 52-244) (Fluoro550) (ABIN7973260)

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRMS1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-BRMS1 Antibody (Fluoro550)

Binding Specificity: AA 52-244

Purpose: Anti-BRMS1 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human BRMS1 shares 93.6%,96% amino acid (aa) sequence identity with mouse,rat BRMS1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BRMS1 recombinant protein (Position: D52-D244). Human BRMS1 shares 93.6% and 96% amino acid (aa) sequence identity with mouse and rat BRMS1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for BRMS1

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Alternative Name: BRMS1

Background:

Background: Breast cancer metastasis-suppressor 1 is a protein that in humans is encoded by the BRMS1 gene. This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Gene Full Name: BRMS1 transcriptional repressor and anoikis regulator

Gene ID: 25855

UniProt: Q9HCU9