Butyrylcholinesterase antibody (AA 263-571) (Cy3)

Catalog No. ABIN7973500

The Rabbit Polyclonal anti-Butyrylcholinesterase antibody is suitable to detect Butyrylcholinesterase in samples from Mouse. It has been validated for FACS.

Quick Overview for Butyrylcholinesterase antibody (AA 263-571) (Cy3) (ABIN7973500)

Target: Butyrylcholinesterase (BCHE)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Butyrylcholinesterase antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-Butyrylcholinesterase Antibody (Cy3)

Binding Specificity: AA 263-571

Purpose: Anti-Butyrylcholinesterase/BCHE Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse BCHE recombinant protein (Position: K263-E571). Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Butyrylcholinesterase

Target: Butyrylcholinesterase (BCHE)

Alternative Name: Bche

Background:

Background: Butyrylcholinesterase (BCHE, or BuChE), also known as pseudocholinesterase or plasma cholinesterase, is a non-specific cholinesterase enzyme that hydrolyses many different choline esters. In humans, it is found primarily in the liver and is encoded by the BCHE gene. Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Gene Full Name: butyrylcholinesterase

Sequence Similarities: Contains 1 CARD domain.

Gene ID: 12038

UniProt: Q03311

Pathways: Peptide Hormone Metabolism