Butyrylcholinesterase antibody (AA 263-571) (HRP)

Catalog No. ABIN7973505

This Rabbit Polyclonal antibody specifically detects Butyrylcholinesterase in WB, ELISA and IHC. It exhibits reactivity toward Mouse.

Quick Overview for Butyrylcholinesterase antibody (AA 263-571) (HRP) (ABIN7973505)

Target: Butyrylcholinesterase (BCHE)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Butyrylcholinesterase antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Butyrylcholinesterase Antibody (HRP)

Binding Specificity: AA 263-571

Purpose: Anti-Butyrylcholinesterase/BCHE Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse BCHE recombinant protein (Position: K263-E571). Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Butyrylcholinesterase

Target: Butyrylcholinesterase (BCHE)

Alternative Name: Bche

Background:

Background: Butyrylcholinesterase (BCHE, or BuChE), also known as pseudocholinesterase or plasma cholinesterase, is a non-specific cholinesterase enzyme that hydrolyses many different choline esters. In humans, it is found primarily in the liver and is encoded by the BCHE gene. Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Gene Full Name: butyrylcholinesterase

Sequence Similarities: Contains 1 CARD domain.

Gene ID: 12038

UniProt: Q03311

Pathways: Peptide Hormone Metabolism