Butyrylcholinesterase antibody (AA 263-571)

Catalog No. ABIN7973509

The Rabbit Polyclonal anti-Butyrylcholinesterase antibody is suitable to detect Butyrylcholinesterase in samples from Mouse. It has been validated for WB.

Quick Overview for Butyrylcholinesterase antibody (AA 263-571) (ABIN7973509)

Target: Butyrylcholinesterase (BCHE)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Butyrylcholinesterase antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-Butyrylcholinesterase Antibody

Binding Specificity: AA 263-571

Purpose: Anti-Butyrylcholinesterase/BCHE Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Characteristics: Anti-Butyrylcholinesterase/BCHE Antibody. Tested in WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse BCHE recombinant protein (Position: K263-E571). Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Butyrylcholinesterase

Target: Butyrylcholinesterase (BCHE)

Alternative Name: Bche

Background:

Background: Butyrylcholinesterase (BCHE, or BuChE), also known as pseudocholinesterase or plasma cholinesterase, is a non-specific cholinesterase enzyme that hydrolyses many different choline esters. In humans, it is found primarily in the liver and is encoded by the BCHE gene. Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Gene Full Name: butyrylcholinesterase

Sequence Similarities: Contains 1 CARD domain.

Molecular Weight: 85-90 kDa

Gene ID: 12038

UniProt: Q03311

Pathways: Peptide Hormone Metabolism