Butyrylcholinesterase antibody (AA 29-602) (APC)

Catalog No. ABIN7973517

This Rabbit Polyclonal antibody specifically detects Butyrylcholinesterase in FACS. It exhibits reactivity toward Human.

Quick Overview for Butyrylcholinesterase antibody (AA 29-602) (APC) (ABIN7973517)

Target: Butyrylcholinesterase (BCHE)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Butyrylcholinesterase antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Butyrylcholinesterase Antibody (APC)

Binding Specificity: AA 29-602

Purpose: Anti-BCHE Antibody APC Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human BCHE shares 80.8% amino acid (aa) sequence identity with mouse BCHE.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BCHE recombinant protein (Position: E29-L602). Human BCHE shares 80.8% amino acid (aa) sequence identity with mouse BCHE.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Butyrylcholinesterase

Target: Butyrylcholinesterase (BCHE)

Alternative Name: BCHE

Background:

Background: This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine.

Gene Full Name: butyrylcholinesterase

Gene ID: 590

UniProt: P06276

Pathways: Peptide Hormone Metabolism