CTBP2 antibody (AA 321-445) (Fluoro647)

Catalog No. ABIN7973717

The Fluoro647-conjugated Mouse Monoclonal anti-CTBP2 antibody (Clone 10E9D2) (ABIN7973717) specifically detects CTBP2 in FACS. The antibody is reactive with Human samples.

Quick Overview for CTBP2 antibody (AA 321-445) (Fluoro647) (ABIN7973717)

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTBP2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Clone: 10E9D2

Product Details anti-CTBP2 Antibody (Fluoro647)

Binding Specificity: AA 321-445

Purpose: Anti-CTBP2 Antibody (monoclonal, 10E9D2) Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: human CTBP2 shares 99.2%,98.4% amino acid (aa) sequence identity with mouse,rat CTBP2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CTBP2 recombinant protein (Position: H321-Q445). human CTBP2 shares 99.2% and 98.4% amino acid (aa) sequence identity with mouse and rat CTBP2, respectively.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CTBP2

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Alternative Name: CTBP2

Background:

Background: The E1a region of group C adenoviruses encodes 2 nearly identical proteins that are largely responsible for the oncogenic properties of adenoviruses. The CTBP1 protein binds to the C-terminal half of these E1A proteins. It's predicted that CTBP2 is a 445-amino acid protein and it is 72 % identical to CTBP1. The CTBP2 gene is mapped to chromosome 10q26.13. CTBP2 is a mammalian corepressor that targets diverse transcriptional regulators. It bounds the short medial portion of delta-EF1 containing the PLDLSL motif and it enhances transrepression activity of delta-EF1.

Gene Full Name: C-terminal binding protein 2

Gene ID: 1488

UniProt: P56545