OB Cadherin antibody (AA 371-796) (PE)

Catalog No. ABIN7973826

This Rabbit Polyclonal antibody specifically detects OB Cadherin in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for OB Cadherin antibody (AA 371-796) (PE) (ABIN7973826)

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OB Cadherin antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-OB Cadherin Antibody (PE)

Binding Specificity: AA 371-796

Purpose: Anti-OB Cadherin/CDH11 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human OB Cadherin/CDH11 recombinant protein (Position: K371-S796).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for OB Cadherin

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Alternative Name: CDH11

Background:

Background: Cadherin-11 is a protein that in humans is encoded by the CDH11 gene. This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Gene Full Name: cadherin 11

Gene ID: 1009

UniProt: P55287