Cadherin 5 antibody (AA 46-285) (HRP)

Catalog No. ABIN7973901

This Rabbit Polyclonal antibody specifically detects Cadherin 5 in WB, IHC and ELISA. It exhibits reactivity toward Mouse and Rat.

Quick Overview for Cadherin 5 antibody (AA 46-285) (HRP) (ABIN7973901)

Target: Cadherin 5 (CDH5)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 5 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Cadherin 5 Antibody (HRP)

Binding Specificity: AA 46-285

Purpose: Anti-VE-Cadherin Cdh5-Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse VE Cadherin recombinant protein (Position: D46-E285).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: Cdh5

Background:

Background: CDH5 (Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. This gene is mapped to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.

Gene Full Name: cadherin 5

Gene ID: 12562

UniProt: P55284

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2