CASK antibody (AA 27-498) (PE)

Catalog No. ABIN7974212

The PE-conjugated Rabbit Polyclonal anti-CASK antibody (ABIN7974212) specifically detects CASK in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CASK antibody (AA 27-498) (PE) (ABIN7974212)

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASK antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CASK Antibody (PE)

Binding Specificity: AA 27-498

Purpose: Anti-CASK Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CASK recombinant protein (Position: R27-D498).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CASK

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Alternative Name: CASK

Background:

Background: Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene. This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, intellectual disability and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: calcium/calmodulin dependent serine protein kinase

Gene ID: 8573

UniProt: O14936

Pathways: Synaptic Vesicle Exocytosis