Calmegin antibody (AA 18-611) (HRP)

Catalog No. ABIN7974265

The Rabbit Polyclonal anti-Calmegin antibody is suitable to detect Calmegin in samples from Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for Calmegin antibody (AA 18-611) (HRP) (ABIN7974265)

Target: Calmegin (CLGN)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calmegin antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Calmegin Antibody (HRP)

Binding Specificity: AA 18-611

Purpose: Anti-Calmegin/Clgn Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Calmegin/Clgn recombinant protein (Position: N18-D611).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Calmegin

Target: Calmegin (CLGN)

Alternative Name: Clgn

Background:

Background: Calmegin, also known as CLGN, is a protein which in humans is encoded by the CLGN gene. This gene belongs to the calreticulin family, which includes calreticulin, calnexin, and calmegin, and encodes a calcium-binding molecular chaperone specifically expressed in pachytene stage male germ cells. It is required for the proper folding of newly synthesized membrane proteins in the endoplasmic reticulum including those critical for sperm migration from the uterus into the oviduct and sperm adhesion to and penetration of the zona pellucida. This gene plays a key role in spermatogenesis and male infertility. Alternative splice variants exist for this gene.

Gene Full Name: calmegin

Gene ID: 12745

UniProt: P52194