Calmegin antibody (AA 18-611)

Catalog No. ABIN7974269

The Rabbit Polyclonal anti-Calmegin antibody (ABIN7974269) specifically detects Calmegin in WB and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Calmegin antibody (AA 18-611) (ABIN7974269)

Target: Calmegin (CLGN)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calmegin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-Calmegin Antibody

Binding Specificity: AA 18-611

Purpose: Anti-Calmegin/Clgn Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Calmegin/Clgn Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Calmegin/Clgn recombinant protein (Position: N18-D611).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Calmegin

Target: Calmegin (CLGN)

Alternative Name: Clgn

Background:

Background: Calmegin, also known as CLGN, is a protein which in humans is encoded by the CLGN gene. This gene belongs to the calreticulin family, which includes calreticulin, calnexin, and calmegin, and encodes a calcium-binding molecular chaperone specifically expressed in pachytene stage male germ cells. It is required for the proper folding of newly synthesized membrane proteins in the endoplasmic reticulum including those critical for sperm migration from the uterus into the oviduct and sperm adhesion to and penetration of the zona pellucida. This gene plays a key role in spermatogenesis and male infertility. Alternative splice variants exist for this gene.

Gene Full Name: calmegin

Molecular Weight: 95 kDa

Gene ID: 12745

UniProt: P52194