CREB3L1 antibody (AA 1-204) (Biotin)

Catalog No. ABIN7974501

This Rabbit Polyclonal antibody specifically detects CREB3L1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for CREB3L1 antibody (AA 1-204) (Biotin) (ABIN7974501)

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB3L1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CREB3L1 Antibody (Biotin)

Binding Specificity: AA 1-204

Purpose: Anti-CREB3L1 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CREB3L1 shares 93.6%,93.1% amino acid (aa) sequence identity with mouse,rat CREB3L1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CREB3L1 recombinant protein (Position: M1-M204). Human CREB3L1 shares 93.6% and 93.1% amino acid (aa) sequence identity with mouse and rat CREB3L1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CREB3L1

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Alternative Name: CREB3L1

Background:

Background: CREB3L1, known as Cyclic AMP-responsive element-binding protein 3-like protein 1, is mapped to 11p11.2. The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements.

Gene Full Name: cAMP responsive element binding protein 3 like 1

Sequence Similarities: Belongs to the bZIP family. ATF subfamily.

Gene ID: 90993

UniProt: Q96BA8

Pathways: Thyroid Hormone Synthesis, Chromatin Binding