CA2 antibody (AA 2-260) (PE)

Catalog No. ABIN7974663

This Rabbit Polyclonal antibody specifically detects CA2 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CA2 antibody (AA 2-260) (PE) (ABIN7974663)

Target: CA2 (Carbonic Anhydrase II (CA2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CA2 Antibody (PE)

Binding Specificity: AA 2-260

Purpose: Anti-Carbonic Anhydrase II/CA2 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CA2 shares 81.1%,80.7% amino acid (aa) sequence identity with mouse,rat CA2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CA2 recombinant protein (Position: S2-K260). Human CA2 shares 81.1% and 80.7% amino acid (aa) sequence identity with mouse and rat CA2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CA2

Target: CA2 (Carbonic Anhydrase II (CA2))

Alternative Name: CA2

Background:

Background: CA2 is a cytosolic enzyme with the highest activity among all known CAs. The carbonic anhydrases (ACs) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. This gene is mapped to 8q22.

Gene Full Name: carbonic anhydrase 2

Gene ID: 760

UniProt: P00918