CA3 antibody (AA 14-235) (APC)

Catalog No. ABIN7974684

This Rabbit Polyclonal antibody specifically detects CA3 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CA3 antibody (AA 14-235) (APC) (ABIN7974684)

Target: CA3 (Carbonic Anhydrase III (CA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-CA3 Antibody (APC)

Binding Specificity: AA 14-235

Purpose: Anti-Carbonic Anhydrase III/CA3 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human CA3 recombinant protein (Position: D14-E235). Human CA3 shares 92.3%,91.4% amino acid (aa) sequence identity with mouse,rat CA3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human CA3 recombinant protein (Position: D14-E235). Human CA3 shares 92.3% and 91.4% amino acid (aa) sequence identity with mouse and rat CA3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CA3

Target: CA3 (Carbonic Anhydrase III (CA3))

Alternative Name: CA3

Background:

Background: Carbonic anhydrase III (CA3) is an enzyme that in humans is encoded by the CA3 gene. CA3 is a member of a multigene family (at least six separate genes are known) that encode carbonic anhydrase isozymes. The gene spans 10.3 kb and contains seven exons and six introns. Using a cDNA clone of the CA3 gene in the study of human-rodent hybrids, the gene was mapped to chromosome 8 which carries a cluster of CA genes. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.

Gene Full Name: carbonic anhydrase 3

Gene ID: 761

UniProt: P07451