CA4 antibody (AA 19-284) (APC)

Catalog No. ABIN7974706

The Rabbit Polyclonal anti-CA4 antibody is suitable to detect CA4 in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for CA4 antibody (AA 19-284) (APC) (ABIN7974706)

Target: CA4 (Carbonic Anhydrase IV (CA4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA4 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-CA4 Antibody (APC)

Binding Specificity: AA 19-284

Purpose: Anti-Carbonic Anhydrase IV/CA4 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human CA IV shares 55.5%,58.9% amino acid (aa) sequence identity with mouse,rat CA IV,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CA IV recombinant protein (Position: A19-S284). Human CA IV shares 55.5% and 58.9% amino acid (aa) sequence identity with mouse and rat CA IV, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CA4

Target: CA4 (Carbonic Anhydrase IV (CA4))

Alternative Name: CA4

Background:

Background: Carbonic anhydrase 4 is an enzyme that in humans is encoded by the CA4 gene. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.

Gene Full Name: carbonic anhydrase 4

Gene ID: 762

UniProt: P22748